The Chacruna species of Psychotria Viridis is traditionally considered the preferred admixture to Ayahuasca. The classical principle admixtures of Ayahuasca and Yagè commonly employed throughout Amazonian Peru, Ecuador and Brazil. Related to the coffee plant in a large genus of over 700 species, Psychotria viridis is a small glabrous tree or shrub reaching 14 foot. It's use has been documented by the Sharanahua and Culina Indian tribes of the southwestern Amazon basin, the Kofá Indians of Amazonian Colombia and Ecuador, the Kashinahua of eastern Peru and western Brazil plus in Tarauacá in the Acre of Brazil amongst others.

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